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Anti -Mannose Receptor Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101797
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

Mannose Receptor rabbit polyclonal

Protein full name

Macrophage mannose receptor 1

Synonyms

CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Mannose Receptor

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membraneEndosome

Uniprot ID

Q61830




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 400-1: 800

lung

IF

Mouse

1: 400-1: 800

lung




Background


CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane glycoprotein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail.




Images



Immunohistochemistry analysis of paraffin-embedded mouse lung with LPS treated for 24h using CD206 (GB113497) at dilution of 1: 800

圖片 2.png


Immunofluorescent analysis of paraformaldehyde-fixed mouse lung with LPS treated for 24h using CD206 (GB113497) at dilution of 1: 800




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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