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Anti -CLIP170 Rabbit pAb

價(jià)格: 在線咨詢(xún)
貨號(hào):
KT011856
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M/R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

CLIP170 rabbit polyclonal antibody

Protein full name

CAP-Gly domain-containing linker protein 1

Synonyms

Cytoplasmic linker protein 170, CLIP-170, Restin, Clip1, Kiaa4046, Rsn

Immunogen

Recombinant protein corresponding to Mouse CLIP170

Isotype

IgG

Purity

Affinity purification

Predicted MW.

162 kDa

Observed MW.

180 kDa

Uniprot ID

P30622, Q922J3, Q9JK25




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain




Background


CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1.




Images


Picture 1.png

Western blot analysis of clip (GB111068) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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