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產品詳情
操作說明
注意事項
Product Information
|
Description |
GRK2 rabbit polyclonal |
|
Protein full name |
Beta-adrenergic receptor kinase 1 |
|
Synonyms |
Beta-ARK-1, G-protein-coupled receptor kinase 2, Grk2, Adrbk1 |
|
Immunogen |
Recombinant protein corresponding to Mouse GRK2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
80 kDa |
|
Observed MW. |
80 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse |
1: 500-1: 1000 |
spleen, lymph nodes |
Background
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Images
|
|
Western blot analysis of GRK2 (GB111115) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室