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產品詳情
操作說明
注意事項
Product Information
|
Description |
TNF Receptor II rabbit polyclonal |
|
Protein full name |
Tumor necrosis factor receptor superfamily member 1B |
|
Synonyms |
Tumor necrosis factor receptor 2, TNFR2, P75, Tumor necrosis factor receptor type II, TNFRII, P80 TNF-alpha receptor,CD120b, Etanercept, TBP-2, TBPII, TNFRSF1B, TNFBR |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse TNF Receptor II |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
48 kDa |
|
Observed MW. |
73 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex, spleen, cerebellum, spinal cord |
Background
The protein encoded by this gene is a member of the TNF-receptor super family. This protein and TNF-receptor 1 form a hetero complex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Images
|
Western blot analysis of TNF Receptor II (GB111014) at dilution of 1: 1000 Lane 1: SW480 cell lysate Lane 2: Mouse brain tissue lysate Lane 3: Mouse cerebral cortex tissue lysate Lane 4: Mouse cerebellum tissue lysate Lane 5: Mouse spinal cord tissue lysate Lane 6: Mouse spleen tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室