Receptor for IL17A . Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F . Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC . Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC . Receptor for IL17C as part of a heterodimeric complex with IL17RE . Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6.
Images
Western blot analysis of IL17RA (GB11289) at dilution of 1: 1000.
Lane 1: HeLa cell lysate
Lane 2: Jurkat cell lysate
Lane 3: Mouse lung tissue lysate
Lane 4: Mouse colon tissue lysate
Lane 5: Rat colon tissue lysate
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .