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Anti -GABA A Receptor alpha 1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011489
產(chǎn)品規(guī)格:
100 μL
Applications:
WB | IHC | IF
Species:
H,M,R | H,M,R
購買數(shù)量:
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Product Information


Description

GABA A Receptor alpha 1 rabbit polyclonal antibody

Protein full name

Gamma-aminobutyric acid type A receptor subunit alpha1

Synonyms

ECA4, EJM, GABA A receptor alpha 1, GABAA receptor alpha 1, GABRA1

Immunogen

Recombinant protein corresponding to Mouse GABA A Receptor alpha 1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane, Secreted

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot ID

P62812




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1500

cerebellum, hippocampus, brain

IHC/IF

Human, Mouse, Rat

1: 300-1: 600

cerebellum, brain




Background


This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.




Images


Picture 1.png Western blot analysis of GABRA1 (GB113973) at dilution of 1: 1000
Picture 2.png Immunohistochemistry of paraffin embedded mouse brain using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)
Picture 3.png Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)
Picture 4.png Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB113973) at dilution of 1: 400 (200x lens)
Picture 5.png Immunohistochemistry of paraffin embedded mouse cerebellum using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)
Picture 6.png Immunohistochemistry of paraffin embedded rat cerebellum using GABRA1 (GB113973) at dilution of 1: 300 (200x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.


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