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Anti -NK-1R Rabbit pAb

價格: 在線咨詢
貨號:
KT011499
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M,R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

NK-1R rabbit polyclonal antibody

Protein full name

Substance-P receptor

Synonyms

Tacr1, TACR1, NK1R, NKIR, SPR, TAC1R, Tachykinin receptor 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TACR1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

46 kDa

Observed MW.

46 kDa

Uniprot ID

P25103, P30548, P14600




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, heart,

spinal cord




Background


The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. It is probably associated with G proteins that activate a phosphatidylinositol calcium second messenger system. The endogenous ligand for this receptor is Substance P. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. The binding of SP to the NK1 receptor has been associated with the transmission of stress signals and pain, the contraction of smooth muscles and inflammation.




Images



Picture 1.png


Western blot analysis of TACR1 (GB11759) at dilution of 1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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