1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, PI(5)P 4-kinase type II alpha, PIP4KII-alpha, PtdIns(5)P-4-kinase isoform 2-alpha, Pip4k2a, Pip5k2a, PIP4K2
Immunogen
Recombinant protein corresponding to Mouse PIP4K2
Isotype
IgG
Purity
Affinity purification
Predicted MW.
46 kDa
Observed MW.
50 kDa
Uniprot ID
P48426, O70172, Q9R0I8
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1:500-1: 1000
brain, spinal cord
Background
This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. Phosphatidylinositol-5, 4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5, 4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity.
Images
Western blot analysis of Pip4k2a (GB111021) at dilution of 1: 500
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .