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Anti -RAB27A Rabbit pAb

價格: 在線咨詢
貨號:
KT012278
產品規格:
100 μL
Applications:
WB
Species:
M/R
購買數量:
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產品詳情 操作說明 注意事項

Product Information


Description

RAB27A rabbit polyclonal antibody

Protein full name

Ras-related protein Rab-27A

Synonyms

Rab27a, Rab27, Ras-related protein Rab-27A, Ras-related protein Rab27A

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse RAB27A

Isotype

IgG

Purity

Affinity purification

Predicted MW.

25 kDa

Observed MW.

28 kDa

Uniprot ID

Q9ERI2, P23640





Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

liver, ovary, kidney



Background


Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.




Images


Picture 1.png

Western blot analysis of RAB27A  at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
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